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Single‐cell RNA‐seq reveals the invasive trajectory and molecular cascades underlying glioblastoma progression

Glioblastoma (GBM) is the most common and aggressive primary brain tumor, in which GBM stem cells (GSCs) were identified to contribute to aggressive phenotypes and poor prognosis. Yet, how GSCs progress to invasive cells remains largely unexplored. Here, we revealed the cell subpopulations with dist...

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Detalles Bibliográficos
Autores principales: Pang, Bo, Xu, Jinyuan, Hu, Jing, Guo, Fenghua, Wan, Linyun, Cheng, Mingjiang, Pang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887585/
https://www.ncbi.nlm.nih.gov/pubmed/31487431
http://dx.doi.org/10.1002/1878-0261.12569