AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage

Enhanced vascular permeability in the lungs can lead to pulmonary edema, impaired gas exchange, and ultimately respiratory failure. While oxygen delivery, mechanical ventilation, and pressure-reducing medications help alleviate these symptoms, they do not treat the underlying disease. Mechanical act...

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Detalles Bibliográficos
Autores principales: Li, Juan, Wen, Amy M., Potla, Ratnakar, Benshirim, Ezekiel, Seebarran, Ariel, Benz, Maximilian A., Henry, Olivier Y. F., Matthews, Benjamin D., Prantil-Baun, Rachelle, Gilpin, Sarah E., Levy, Oren, Ingber, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887658/
https://www.ncbi.nlm.nih.gov/pubmed/31803860
http://dx.doi.org/10.1063/1.5122967

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