No evidence for interactions of dimethylfumarate (DMF) and its main metabolite monomethylfumarate (MMF) with human cytochrome P450 (CYP) enzymes and the P‐glycoprotein (P‐gp) drug transporter

Dimethylfumarate (DMF) has long been used as part of a fixed combination of fumaric acid esters (FAE) in some European countries and is now available as an oral monotherapy for psoriasis. The present investigation determined whether DMF and its main metabolite monomethylfumarate (MMF) interact with...

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Detalles Bibliográficos
Autores principales: Aubets, Jordi, Jansat, Josep‐Maria, Salva, Miquel, Birks, Vicky M., Cole, Richard J., Lewis, Jenny, Pitcher, Annabell, Hall, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887663/
https://www.ncbi.nlm.nih.gov/pubmed/31832203
http://dx.doi.org/10.1002/prp2.540

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