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Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma

BACKGROUND: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video‐assisted thoracoscopic surgical (VATS) p...

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Autores principales: Isaacs, K. E., Belete, S., Miller, B. J., Di Marco, A. N., Kirby, S., Barwick, T., Tolley, N. S., Anderson, J. R., Palazzo, F. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887896/
https://www.ncbi.nlm.nih.gov/pubmed/31832580
http://dx.doi.org/10.1002/bjs5.50207
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author Isaacs, K. E.
Belete, S.
Miller, B. J.
Di Marco, A. N.
Kirby, S.
Barwick, T.
Tolley, N. S.
Anderson, J. R.
Palazzo, F. F.
author_facet Isaacs, K. E.
Belete, S.
Miller, B. J.
Di Marco, A. N.
Kirby, S.
Barwick, T.
Tolley, N. S.
Anderson, J. R.
Palazzo, F. F.
author_sort Isaacs, K. E.
collection PubMed
description BACKGROUND: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video‐assisted thoracoscopic surgical (VATS) parathyroidectomy represents a modern alternative approach to this problem. METHODS: Information on patients undergoing VATS was obtained from a specific database, including clinical presentation, biochemistry, preoperative imaging, surgical approach and patient outcomes. A comprehensive literature review was undertaken to draw comparisons with other publications. RESULTS: Over a 2‐year period, nine patients underwent VATS parathyroidectomy for sporadic PHPT. Five patients had persistent PHPT following previous unsuccessful parathyroidectomy via cervicotomy, and four had had no previous parathyroid surgery. The median duration of surgery was 90 (range 60–160) min. Eight patients were cured biochemically, with no major complications. One patient required conversion to a median sternotomy for removal of a thymoma that had resulted in false‐positive preoperative imaging. CONCLUSION: With appropriate preoperative imaging, multidisciplinary input and expertise, VATS parathyroidectomy is an effective, safe and well tolerated approach to ectopic mediastinal parathyroid adenoma.
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spelling pubmed-68878962019-12-12 Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma Isaacs, K. E. Belete, S. Miller, B. J. Di Marco, A. N. Kirby, S. Barwick, T. Tolley, N. S. Anderson, J. R. Palazzo, F. F. BJS Open Original Articles BACKGROUND: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video‐assisted thoracoscopic surgical (VATS) parathyroidectomy represents a modern alternative approach to this problem. METHODS: Information on patients undergoing VATS was obtained from a specific database, including clinical presentation, biochemistry, preoperative imaging, surgical approach and patient outcomes. A comprehensive literature review was undertaken to draw comparisons with other publications. RESULTS: Over a 2‐year period, nine patients underwent VATS parathyroidectomy for sporadic PHPT. Five patients had persistent PHPT following previous unsuccessful parathyroidectomy via cervicotomy, and four had had no previous parathyroid surgery. The median duration of surgery was 90 (range 60–160) min. Eight patients were cured biochemically, with no major complications. One patient required conversion to a median sternotomy for removal of a thymoma that had resulted in false‐positive preoperative imaging. CONCLUSION: With appropriate preoperative imaging, multidisciplinary input and expertise, VATS parathyroidectomy is an effective, safe and well tolerated approach to ectopic mediastinal parathyroid adenoma. John Wiley & Sons, Ltd 2019-08-19 /pmc/articles/PMC6887896/ /pubmed/31832580 http://dx.doi.org/10.1002/bjs5.50207 Text en © 2019 The Authors. BJS Open published by John Wiley & Sons Ltd on behalf of BJS Society Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Isaacs, K. E.
Belete, S.
Miller, B. J.
Di Marco, A. N.
Kirby, S.
Barwick, T.
Tolley, N. S.
Anderson, J. R.
Palazzo, F. F.
Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma
title Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma
title_full Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma
title_fullStr Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma
title_full_unstemmed Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma
title_short Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma
title_sort video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887896/
https://www.ncbi.nlm.nih.gov/pubmed/31832580
http://dx.doi.org/10.1002/bjs5.50207
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