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Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma
BACKGROUND: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video‐assisted thoracoscopic surgical (VATS) p...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887896/ https://www.ncbi.nlm.nih.gov/pubmed/31832580 http://dx.doi.org/10.1002/bjs5.50207 |
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author | Isaacs, K. E. Belete, S. Miller, B. J. Di Marco, A. N. Kirby, S. Barwick, T. Tolley, N. S. Anderson, J. R. Palazzo, F. F. |
author_facet | Isaacs, K. E. Belete, S. Miller, B. J. Di Marco, A. N. Kirby, S. Barwick, T. Tolley, N. S. Anderson, J. R. Palazzo, F. F. |
author_sort | Isaacs, K. E. |
collection | PubMed |
description | BACKGROUND: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video‐assisted thoracoscopic surgical (VATS) parathyroidectomy represents a modern alternative approach to this problem. METHODS: Information on patients undergoing VATS was obtained from a specific database, including clinical presentation, biochemistry, preoperative imaging, surgical approach and patient outcomes. A comprehensive literature review was undertaken to draw comparisons with other publications. RESULTS: Over a 2‐year period, nine patients underwent VATS parathyroidectomy for sporadic PHPT. Five patients had persistent PHPT following previous unsuccessful parathyroidectomy via cervicotomy, and four had had no previous parathyroid surgery. The median duration of surgery was 90 (range 60–160) min. Eight patients were cured biochemically, with no major complications. One patient required conversion to a median sternotomy for removal of a thymoma that had resulted in false‐positive preoperative imaging. CONCLUSION: With appropriate preoperative imaging, multidisciplinary input and expertise, VATS parathyroidectomy is an effective, safe and well tolerated approach to ectopic mediastinal parathyroid adenoma. |
format | Online Article Text |
id | pubmed-6887896 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-68878962019-12-12 Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma Isaacs, K. E. Belete, S. Miller, B. J. Di Marco, A. N. Kirby, S. Barwick, T. Tolley, N. S. Anderson, J. R. Palazzo, F. F. BJS Open Original Articles BACKGROUND: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video‐assisted thoracoscopic surgical (VATS) parathyroidectomy represents a modern alternative approach to this problem. METHODS: Information on patients undergoing VATS was obtained from a specific database, including clinical presentation, biochemistry, preoperative imaging, surgical approach and patient outcomes. A comprehensive literature review was undertaken to draw comparisons with other publications. RESULTS: Over a 2‐year period, nine patients underwent VATS parathyroidectomy for sporadic PHPT. Five patients had persistent PHPT following previous unsuccessful parathyroidectomy via cervicotomy, and four had had no previous parathyroid surgery. The median duration of surgery was 90 (range 60–160) min. Eight patients were cured biochemically, with no major complications. One patient required conversion to a median sternotomy for removal of a thymoma that had resulted in false‐positive preoperative imaging. CONCLUSION: With appropriate preoperative imaging, multidisciplinary input and expertise, VATS parathyroidectomy is an effective, safe and well tolerated approach to ectopic mediastinal parathyroid adenoma. John Wiley & Sons, Ltd 2019-08-19 /pmc/articles/PMC6887896/ /pubmed/31832580 http://dx.doi.org/10.1002/bjs5.50207 Text en © 2019 The Authors. BJS Open published by John Wiley & Sons Ltd on behalf of BJS Society Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Isaacs, K. E. Belete, S. Miller, B. J. Di Marco, A. N. Kirby, S. Barwick, T. Tolley, N. S. Anderson, J. R. Palazzo, F. F. Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma |
title | Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma |
title_full | Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma |
title_fullStr | Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma |
title_full_unstemmed | Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma |
title_short | Video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma |
title_sort | video‐assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887896/ https://www.ncbi.nlm.nih.gov/pubmed/31832580 http://dx.doi.org/10.1002/bjs5.50207 |
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