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Rosiglitazone polarizes microglia and protects against pilocarpine‐induced status epilepticus

AIMS: Activated microglia have been found in the forebrains and hippocampi of temporal lobe epilepsy (TLE) patients and status epileptic (SE) animal models. The peroxisome proliferator‐activated receptor γ (PPAR γ) agonist rosiglitazone has been shown to prevent microglial activation. However, its r...

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Detalles Bibliográficos
Autores principales: Peng, Jing, Wang, Kan, Xiang, Weiwei, Li, Yan, Hao, Yong, Guan, Yangtai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887926/
https://www.ncbi.nlm.nih.gov/pubmed/31729170
http://dx.doi.org/10.1111/cns.13265