Defining Signatures of Arm-Wise Copy Number Change and Their Associated Drivers in Kidney Cancers

Using pan-cancer data from The Cancer Genome Atlas (TCGA), we investigated how patterns in copy number alterations in cancer cells vary both by tissue type and as a function of genetic alteration. We find that patterns in both chromosomal ploidy and individual arm copy number are dependent on tumour...

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Detalles Bibliográficos
Autores principales: Benstead-Hume, Graeme, Wooller, Sarah K., Downs, Jessica A, Pearl, Frances M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887958/
https://www.ncbi.nlm.nih.gov/pubmed/31744086
http://dx.doi.org/10.3390/ijms20225762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887958/
https://www.ncbi.nlm.nih.gov/pubmed/31744086
http://dx.doi.org/10.3390/ijms20225762

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