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Defining Signatures of Arm-Wise Copy Number Change and Their Associated Drivers in Kidney Cancers
Using pan-cancer data from The Cancer Genome Atlas (TCGA), we investigated how patterns in copy number alterations in cancer cells vary both by tissue type and as a function of genetic alteration. We find that patterns in both chromosomal ploidy and individual arm copy number are dependent on tumour...
Autores principales: | Benstead-Hume, Graeme, Wooller, Sarah K., Downs, Jessica A, Pearl, Frances M. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887958/ https://www.ncbi.nlm.nih.gov/pubmed/31744086 http://dx.doi.org/10.3390/ijms20225762 |
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