Novel Crizotinib–GnRH Conjugates Revealed the Significance of Lysosomal Trapping in GnRH-Based Drug Delivery Systems

Several promising anti-cancer drug–GnRH (gonadotropin-releasing hormone) conjugates have been developed in the last two decades, although none of them have been approved for clinical use yet. Crizotinib is an effective multi-target kinase inhibitor, approved against anaplastic lymphoma kinase (ALK)-...

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Detalles Bibliográficos
Autores principales: Murányi, József, Varga, Attila, Gyulavári, Pál, Pénzes, Kinga, Németh, Csilla E., Csala, Miklós, Pethő, Lilla, Csámpai, Antal, Halmos, Gábor, Peták, István, Vályi-Nagy, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888004/
https://www.ncbi.nlm.nih.gov/pubmed/31717403
http://dx.doi.org/10.3390/ijms20225590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888004/
https://www.ncbi.nlm.nih.gov/pubmed/31717403
http://dx.doi.org/10.3390/ijms20225590

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