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Changes in Calcium Homeostasis and Gene Expression Implicated in Epilepsy in Hippocampi of Mice Overexpressing ORAI1

Previously, we showed that the overexpression of ORAI1 calcium channel in neurons of murine brain led to spontaneous occurrence of seizure-like events in aged animals of transgenic line FVB/NJ-Tg(ORAI1)Ibd (Nencki Institute of Experimental Biology). We aimed to identify the mechanism that is respons...

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Detalles Bibliográficos
Autores principales: Majewski, Lukasz, Wojtas, Bartosz, Maciąg, Filip, Kuznicki, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888010/
https://www.ncbi.nlm.nih.gov/pubmed/31698854
http://dx.doi.org/10.3390/ijms20225539