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Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China

Chronic kidney disease (CKD) is a global major public health problem. Almost all of previous studies evaluating the prevalence of CKD focused on adults, while studies among the elderly were relatively rare, especially in China. The aim of this study was to investigate the prevalence and associated r...

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Autores principales: Ji, Andong, Pan, Chunlei, Wang, Hongxia, Jin, Zhezhen, Lee, Joseph H., Wu, Qincheng, Jiang, Qixiao, Cui, Lianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888049/
https://www.ncbi.nlm.nih.gov/pubmed/31717585
http://dx.doi.org/10.3390/ijerph16224383
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author Ji, Andong
Pan, Chunlei
Wang, Hongxia
Jin, Zhezhen
Lee, Joseph H.
Wu, Qincheng
Jiang, Qixiao
Cui, Lianhua
author_facet Ji, Andong
Pan, Chunlei
Wang, Hongxia
Jin, Zhezhen
Lee, Joseph H.
Wu, Qincheng
Jiang, Qixiao
Cui, Lianhua
author_sort Ji, Andong
collection PubMed
description Chronic kidney disease (CKD) is a global major public health problem. Almost all of previous studies evaluating the prevalence of CKD focused on adults, while studies among the elderly were relatively rare, especially in China. The aim of this study was to investigate the prevalence and associated risk factors of CKD among the elderly in Qingdao, China. This was a cross-sectional study with 38,038 inhabitants (aged 60–109) randomly recruited in Qingdao, China. All participants were required to complete a questionnaire for their demographic characteristics. Blood and urine samples of participants were collected, and the albumin and creatinine levels were measured for albuminuria and estimated glomerular filtration rate (eGFR) assessment. The associations between risk factors and indicators of kidney damage were analyzed by logistic regression. A total of 34,588 inhabitants completed the survey. The overall prevalence of CKD was 11.41% (95% confidence interval (CI): 11.07–11.74%) in the elders from Qingdao in 2016. The prevalence of albuminuria and low eGFR (<60 mL/min per 1·73 m²) were 8.47% (95% CI: 8.17–8.76%) and 3.98% (95% CI: 3.78–4.19%), respectively. Older age, hypertension, diabetes, anemia, hyperuricemia, hyperhomocysteinemia, hypertriglyceridemia, obesity, and LDL-C ≥ 4.1 mmol/L were independently associated with the presence of CKD. In conclusion, common chronic non-communicable diseases, including hypertension, diabetes, obesity, hyperhomocysteinemia, hyperuricemia, and hypertriglyceridemia, were associated with greater prevalence of CKD.
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spelling pubmed-68880492019-12-09 Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China Ji, Andong Pan, Chunlei Wang, Hongxia Jin, Zhezhen Lee, Joseph H. Wu, Qincheng Jiang, Qixiao Cui, Lianhua Int J Environ Res Public Health Article Chronic kidney disease (CKD) is a global major public health problem. Almost all of previous studies evaluating the prevalence of CKD focused on adults, while studies among the elderly were relatively rare, especially in China. The aim of this study was to investigate the prevalence and associated risk factors of CKD among the elderly in Qingdao, China. This was a cross-sectional study with 38,038 inhabitants (aged 60–109) randomly recruited in Qingdao, China. All participants were required to complete a questionnaire for their demographic characteristics. Blood and urine samples of participants were collected, and the albumin and creatinine levels were measured for albuminuria and estimated glomerular filtration rate (eGFR) assessment. The associations between risk factors and indicators of kidney damage were analyzed by logistic regression. A total of 34,588 inhabitants completed the survey. The overall prevalence of CKD was 11.41% (95% confidence interval (CI): 11.07–11.74%) in the elders from Qingdao in 2016. The prevalence of albuminuria and low eGFR (<60 mL/min per 1·73 m²) were 8.47% (95% CI: 8.17–8.76%) and 3.98% (95% CI: 3.78–4.19%), respectively. Older age, hypertension, diabetes, anemia, hyperuricemia, hyperhomocysteinemia, hypertriglyceridemia, obesity, and LDL-C ≥ 4.1 mmol/L were independently associated with the presence of CKD. In conclusion, common chronic non-communicable diseases, including hypertension, diabetes, obesity, hyperhomocysteinemia, hyperuricemia, and hypertriglyceridemia, were associated with greater prevalence of CKD. MDPI 2019-11-09 2019-11 /pmc/articles/PMC6888049/ /pubmed/31717585 http://dx.doi.org/10.3390/ijerph16224383 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ji, Andong
Pan, Chunlei
Wang, Hongxia
Jin, Zhezhen
Lee, Joseph H.
Wu, Qincheng
Jiang, Qixiao
Cui, Lianhua
Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China
title Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China
title_full Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China
title_fullStr Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China
title_full_unstemmed Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China
title_short Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China
title_sort prevalence and associated risk factors of chronic kidney disease in an elderly population from eastern china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888049/
https://www.ncbi.nlm.nih.gov/pubmed/31717585
http://dx.doi.org/10.3390/ijerph16224383
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