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Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China
Chronic kidney disease (CKD) is a global major public health problem. Almost all of previous studies evaluating the prevalence of CKD focused on adults, while studies among the elderly were relatively rare, especially in China. The aim of this study was to investigate the prevalence and associated r...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888049/ https://www.ncbi.nlm.nih.gov/pubmed/31717585 http://dx.doi.org/10.3390/ijerph16224383 |
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author | Ji, Andong Pan, Chunlei Wang, Hongxia Jin, Zhezhen Lee, Joseph H. Wu, Qincheng Jiang, Qixiao Cui, Lianhua |
author_facet | Ji, Andong Pan, Chunlei Wang, Hongxia Jin, Zhezhen Lee, Joseph H. Wu, Qincheng Jiang, Qixiao Cui, Lianhua |
author_sort | Ji, Andong |
collection | PubMed |
description | Chronic kidney disease (CKD) is a global major public health problem. Almost all of previous studies evaluating the prevalence of CKD focused on adults, while studies among the elderly were relatively rare, especially in China. The aim of this study was to investigate the prevalence and associated risk factors of CKD among the elderly in Qingdao, China. This was a cross-sectional study with 38,038 inhabitants (aged 60–109) randomly recruited in Qingdao, China. All participants were required to complete a questionnaire for their demographic characteristics. Blood and urine samples of participants were collected, and the albumin and creatinine levels were measured for albuminuria and estimated glomerular filtration rate (eGFR) assessment. The associations between risk factors and indicators of kidney damage were analyzed by logistic regression. A total of 34,588 inhabitants completed the survey. The overall prevalence of CKD was 11.41% (95% confidence interval (CI): 11.07–11.74%) in the elders from Qingdao in 2016. The prevalence of albuminuria and low eGFR (<60 mL/min per 1·73 m²) were 8.47% (95% CI: 8.17–8.76%) and 3.98% (95% CI: 3.78–4.19%), respectively. Older age, hypertension, diabetes, anemia, hyperuricemia, hyperhomocysteinemia, hypertriglyceridemia, obesity, and LDL-C ≥ 4.1 mmol/L were independently associated with the presence of CKD. In conclusion, common chronic non-communicable diseases, including hypertension, diabetes, obesity, hyperhomocysteinemia, hyperuricemia, and hypertriglyceridemia, were associated with greater prevalence of CKD. |
format | Online Article Text |
id | pubmed-6888049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-68880492019-12-09 Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China Ji, Andong Pan, Chunlei Wang, Hongxia Jin, Zhezhen Lee, Joseph H. Wu, Qincheng Jiang, Qixiao Cui, Lianhua Int J Environ Res Public Health Article Chronic kidney disease (CKD) is a global major public health problem. Almost all of previous studies evaluating the prevalence of CKD focused on adults, while studies among the elderly were relatively rare, especially in China. The aim of this study was to investigate the prevalence and associated risk factors of CKD among the elderly in Qingdao, China. This was a cross-sectional study with 38,038 inhabitants (aged 60–109) randomly recruited in Qingdao, China. All participants were required to complete a questionnaire for their demographic characteristics. Blood and urine samples of participants were collected, and the albumin and creatinine levels were measured for albuminuria and estimated glomerular filtration rate (eGFR) assessment. The associations between risk factors and indicators of kidney damage were analyzed by logistic regression. A total of 34,588 inhabitants completed the survey. The overall prevalence of CKD was 11.41% (95% confidence interval (CI): 11.07–11.74%) in the elders from Qingdao in 2016. The prevalence of albuminuria and low eGFR (<60 mL/min per 1·73 m²) were 8.47% (95% CI: 8.17–8.76%) and 3.98% (95% CI: 3.78–4.19%), respectively. Older age, hypertension, diabetes, anemia, hyperuricemia, hyperhomocysteinemia, hypertriglyceridemia, obesity, and LDL-C ≥ 4.1 mmol/L were independently associated with the presence of CKD. In conclusion, common chronic non-communicable diseases, including hypertension, diabetes, obesity, hyperhomocysteinemia, hyperuricemia, and hypertriglyceridemia, were associated with greater prevalence of CKD. MDPI 2019-11-09 2019-11 /pmc/articles/PMC6888049/ /pubmed/31717585 http://dx.doi.org/10.3390/ijerph16224383 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ji, Andong Pan, Chunlei Wang, Hongxia Jin, Zhezhen Lee, Joseph H. Wu, Qincheng Jiang, Qixiao Cui, Lianhua Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China |
title | Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China |
title_full | Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China |
title_fullStr | Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China |
title_full_unstemmed | Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China |
title_short | Prevalence and Associated Risk Factors of Chronic Kidney Disease in an Elderly Population from Eastern China |
title_sort | prevalence and associated risk factors of chronic kidney disease in an elderly population from eastern china |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888049/ https://www.ncbi.nlm.nih.gov/pubmed/31717585 http://dx.doi.org/10.3390/ijerph16224383 |
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