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HUNK Phosphorylates Rubicon to Support Autophagy

Background: Autophagy is a catabolic cellular recycling pathway that is essential for maintaining intracellular homeostasis. Autophagosome formation is achieved via the coordination of the Beclin-1 protein complex. Rubicon is a Beclin-1 associated protein that suppresses autophagy by impairing the a...

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Detalles Bibliográficos
Autores principales: Zambrano, Joelle N., Eblen, Scott T., Abt, Melissa, Rhett, J. Matthew, Muise-Helmericks, Robin, Yeh, Elizabeth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888122/
https://www.ncbi.nlm.nih.gov/pubmed/31752345
http://dx.doi.org/10.3390/ijms20225813