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Acute Liver Injury after CCl(4) Administration Is Independent of Smad7 Expression in Myeloid Cells

Myeloid cells are essential for the initiation and termination of innate and adaptive immunity that create homeostasis in the liver. Smad7 is an inhibitor of the transforming growth factor β (TGF-β) signaling pathway, which regulates inflammatory cellular processes. Knockdown of Smad7 in hepatocytes...

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Detalles Bibliográficos
Autores principales:	Endig, Jessica, Unrau, Ludmilla, Sprezyna, Paulina, Rading, Sebasting, Karsak, Meliha, Goltz, Diane, Heukamp, Lukas C., Tiegs, Gisa, Diehl, Linda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888233/ https://www.ncbi.nlm.nih.gov/pubmed/31698731 http://dx.doi.org/10.3390/ijms20225528

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