A Double Negative Feedback Loop between mTORC1 and AMPK Kinases Guarantees Precise Autophagy Induction upon Cellular Stress

Cellular homeostasis is controlled by an evolutionary conserved cellular digestive process called autophagy. This mechanism is tightly regulated by the two sensor elements called mTORC1 and AMPK. mTORC1 is one of the master regulators of proteostasis, while AMPK maintains cellular energy homeostasis...

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Detalles Bibliográficos
Autores principales: Holczer, Marianna, Hajdú, Bence, Lőrincz, Tamás, Szarka, András, Bánhegyi, Gábor, Kapuy, Orsolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888297/
https://www.ncbi.nlm.nih.gov/pubmed/31703252
http://dx.doi.org/10.3390/ijms20225543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888297/
https://www.ncbi.nlm.nih.gov/pubmed/31703252
http://dx.doi.org/10.3390/ijms20225543

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