AEG-1/miR-221 Axis Cooperatively Regulates the Progression of Hepatocellular Carcinoma by Targeting PTEN/PI3K/AKT Signaling Pathway

Hepatocellular carcinoma (HCC) is the third leading malignancy worldwide, causing mortality in children and adults. AEG-1 is functioned as a scaffold protein for the proper assembly of RNA-induced silencing complex (RISC) to optimize or increase its activity. The increased activity of oncogenic miRN...

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Detalles Bibliográficos
Autores principales: Kannan, Maheshkumar, Jayamohan, Sridharan, Moorthy, Rajesh Kannan, Chabattula, Siva Chander, Ganeshan, Mathan, Arockiam, Antony Joseph Velanganni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888527/
https://www.ncbi.nlm.nih.gov/pubmed/31698701
http://dx.doi.org/10.3390/ijms20225526

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