Druggable Biochemical Pathways and Potential Therapeutic Alternatives to Target Leukemic Stem Cells and Eliminate the Residual Disease in Chronic Myeloid Leukemia

Chronic Myeloid Leukemia (CML) is a disease arising in stem cells expressing the BCR-ABL oncogenic tyrosine kinase that transforms one Hematopoietic stem/progenitor Cell into a Leukemic Stem Cell (LSC) at the origin of differentiated and proliferating leukemic cells in the bone marrow (BM). CML-LSCs...

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Detalles Bibliográficos
Autores principales: Muselli, Fabien, Peyron, Jean-François, Mary, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888542/
https://www.ncbi.nlm.nih.gov/pubmed/31717629
http://dx.doi.org/10.3390/ijms20225616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888542/
https://www.ncbi.nlm.nih.gov/pubmed/31717629
http://dx.doi.org/10.3390/ijms20225616

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