Cargando…

Role of the Balance of Akt and MAPK Pathways in the Exercise-Regulated Phenotype Switching in Spontaneously Hypertensive Rats

The mechanisms regulating vascular smooth muscle cell (VSMC) phenotype switching and the critical signal modulation affecting the VSMCs remain controversial. Physical exercise acts as an effective drug in preventing elevated blood pressure and improving vascular function. This study was designed to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lin, Zhang, Yanyan, Wu, Ying, Yu, Jingjing, Zhang, Yimin, Zeng, Fanxing, Shi, Lijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888552/ https://www.ncbi.nlm.nih.gov/pubmed/31766280 http://dx.doi.org/10.3390/ijms20225690

Ejemplares similares

Morphological Study of the Effect of Aerobic Exercise on Organs and Arteries in Spontaneously Hypertensive Rats
por: Xiong, Yingzhe, et al.
Publicado: (2021)

Qiliqiangxin Enhances Cardiac Glucose Metabolism and Improves Diastolic Function in Spontaneously Hypertensive Rats
por: Wang, Jingfeng, et al.
Publicado: (2017)

Differential microRNA expression profiles and bioinformatics analysis between young and aging spontaneously hypertensive rats
por: Wang, Jingfeng, et al.
Publicado: (2018)

Dissecting the Metabolic Phenotype of the Antihypertensive Effects of Five Uncaria Species on Spontaneously Hypertensive Rats
por: Feng, Zijin, et al.
Publicado: (2019)

Pancreatic Microcirculation Profiles in the Progression of Hypertension in Spontaneously Hypertensive Rats
por: Liu, Mingming, et al.
Publicado: (2020)

Lymphatic microcirculation profile in the progression of hypertension in spontaneously hypertensive rats
por: Wang, Bing, et al.
Publicado: (2021)

Inhibition of Rho/ROCK signaling pathway participates in the cardiac protection of exercise training in spontaneously hypertensive rats
por: Li, Mengwei, et al.
Publicado: (2022)

Effect of exercise training on the FNDC5/BDNF pathway in spontaneously hypertensive rats
por: Wang, Tao, et al.
Publicado: (2019)

Post‐exercise hypotension in male spontaneously hypertensive rats: The issue of calculation method
por: Krzesiak, Amandine, et al.
Publicado: (2023)

Glycyrrhetinic Acid Improves Insulin-Response Pathway by Regulating the Balance between the Ras/MAPK and PI3K/Akt Pathways
por: Zhang, Yuan, et al.
Publicado: (2019)

Roles of MAPK and Spindle Assembly Checkpoint in Spontaneous Activation and MIII Arrest of Rat Oocytes
por: Cui, Wei, et al.
Publicado: (2012)

Irisin Lowers Blood Pressure by Improvement of Endothelial Dysfunction via AMPK‐Akt‐eNOS‐NO Pathway in the Spontaneously Hypertensive Rat
por: Fu, Jinjuan, et al.
Publicado: (2016)

Brain Temperature in Spontaneously Hypertensive Rats during Physical Exercise in Temperate and Warm Environments
por: Drummond, Lucas Rios, et al.
Publicado: (2016)

A single resistance exercise session improves myocardial contractility in spontaneously hypertensive rats
por: Fernandes, A.A., et al.
Publicado: (2015)

Low‐intensity aerobic exercise improves cardiac remodelling of adult spontaneously hypertensive rats
por: Pagan, Luana U., et al.
Publicado: (2019)

An Overview of miRNAs Involved in PASMC Phenotypic Switching in Pulmonary Hypertension
por: Zhang, Weifang, et al.
Publicado: (2021)

Effects of a catechins-enriched diet associated with moderate physical exercise in the prevention of hypertension in spontaneously hypertensive rats
por: Del Seppia, Cristina, et al.
Publicado: (2022)

Synemin promotes pulmonary artery smooth muscle cell phenotypic switch in shunt‐induced pulmonary arterial hypertension
por: Zhou, Jingjing
Publicado: (2022)

CRLF1 promotes malignant phenotypes of papillary thyroid carcinoma by activating the MAPK/ERK and PI3K/AKT pathways
por: Yu, Shi-Tong, et al.
Publicado: (2018)

Transfer of Th17 from Adult Spontaneous Hypertensive Rats Accelerates Development of Hypertension in Juvenile Spontaneous Hypertensive Rats
por: Kim, Jee Young, et al.
Publicado: (2021)

Mechanism of arterial injury exacerbated by hyperhomocysteinemia in spontaneously hypertensive rats
por: Zhang, Lihua, et al.
Publicado: (2023)

Functional status of microvascular vasomotion is impaired in spontaneously hypertensive rat
por: Liu, Mingming, et al.
Publicado: (2017)

Proteomic Response to Acupuncture Treatment in Spontaneously Hypertensive Rats
por: Lai, Xinsheng, et al.
Publicado: (2012)

Age-related changes in hypertensive brain damage in the hippocampi of spontaneously hypertensive rats
por: LI, YALI, et al.
Publicado: (2016)

Plasmodium falciparum strains spontaneously switch invasion phenotype in suspension culture
por: Awandare, Gordon A., et al.
Publicado: (2018)

Effect of Gut Microbiota on the Pharmacokinetics of Nifedipine in Spontaneously Hypertensive Rats
por: Zhou, Rong, et al.
Publicado: (2023)

Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension
por: Neves, Rodrigo Vanerson Passos, et al.
Publicado: (2016)

Forced Exercise Enhances Functional Recovery after Focal Cerebral Ischemia in Spontaneously Hypertensive Rats
por: Park, Sookyoung, et al.
Publicado: (2012)

Effects of Exercise Training on PPARβ/δ Expression in Skeletal Muscle of Rats with Spontaneous Hypertension
por: YANG, MINGXUAN, et al.
Publicado: (2022)

Establishment of the circadian metabolic phenotype strategy in spontaneously hypertensive rats: a dynamic metabolomics study
por: Wang, Huanjun, et al.
Publicado: (2020)

G-CSF Protects Human Brain Vascular Endothelial Cells Injury Induced by High Glucose, Free Fatty Acids and Hypoxia through MAPK and Akt Signaling
por: Su, Jingjing, et al.
Publicado: (2015)

Effect of Yishenjiangyafang on Plasma Metabolomics in Senile Spontaneously Hypertensive Rats
por: Zhang, Lei, et al.
Publicado: (2021)

Effect of Chinese Medicine Xinmaitong on Blood Pressure in Spontaneously Hypertensive Rats
por: Zhang, Bin, et al.
Publicado: (2020)

Androgen interacts with exercise through the mTOR pathway to induce skeletal muscle hypertrophy
por: Zeng, Fanxing, et al.
Publicado: (2017)

A new approach to identifying hypertension-associated genes in the mesenteric artery of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats
por: Ikawa, Takashi, et al.
Publicado: (2019)

Serum Amyloid A Induces a Vascular Smooth Muscle Cell Phenotype Switch through the p38 MAPK Signaling Pathway
por: Zhang, Xincai, et al.
Publicado: (2017)

GPR30 Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells via Activating the AKT and ERK Pathways
por: Zha, Binshan, et al.
Publicado: (2020)

Mechanisms of Improved Aortic Stiffness by Arotinolol in Spontaneously Hypertensive Rats
por: Zhou, Wugang, et al.
Publicado: (2014)

Ameliorated biomechanical properties of carotid arteries by puerarin in spontaneously hypertensive rats
por: Fang, Xiaoxia, et al.
Publicado: (2021)

Effect of exercise training on Ca(2+) release units of left ventricular myocytes of spontaneously hypertensive rats
por: Carneiro-Júnior, M.A., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ileiphnnoq8hj2b7mamb0j0pe3