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APOBEC3-Mediated RNA Editing in Breast Cancer is Associated with Heightened Immune Activity and Improved Survival

APOBEC3 enzymes contribute significantly to DNA mutagenesis in cancer. These enzymes are also capable of converting C bases at specific positions of RNAs to U. However, the prevalence and significance of this C-to-U RNA editing in any cancer is currently unknown. We developed a bioinformatics workfl...

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Detalles Bibliográficos
Autores principales: Asaoka, Mariko, Ishikawa, Takashi, Takabe, Kazuaki, Patnaik, Santosh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888598/
https://www.ncbi.nlm.nih.gov/pubmed/31717692
http://dx.doi.org/10.3390/ijms20225621

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