Cargando…

Neuronal Death in the Contralateral Un-Injured Retina after Unilateral Axotomy: Role of Microglial Cells

For years it has been known that unilateral optic nerve lesions induce a bilateral response that causes an inflammatory and microglial response in the contralateral un-injured retinas. Whether this contralateral response involves retinal ganglion cell (RGC) loss is still unknown. We have analyzed th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lucas-Ruiz, Fernando, Galindo-Romero, Caridad, Rodríguez-Ramírez, Kristy T., Vidal-Sanz, Manuel, Agudo-Barriuso, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888632/ https://www.ncbi.nlm.nih.gov/pubmed/31731684 http://dx.doi.org/10.3390/ijms20225733

Ejemplares similares

Axonal Injuries Cast Long Shadows: Long Term Glial Activation in Injured and Contralateral Retinas after Unilateral Axotomy
por: González-Riquelme, María José, et al.
Publicado: (2021)

Mechanisms implicated in the contralateral effect in the central nervous system after unilateral injury: focus on the visual system
por: Lucas-Ruiz, Fernando, et al.
Publicado: (2021)

Systemic and Intravitreal Antagonism of the TNFR1 Signaling Pathway Delays Axotomy-Induced Retinal Ganglion Cell Loss
por: Lucas-Ruiz, Fernando, et al.
Publicado: (2019)

Microglial dynamics after axotomy-induced retinal ganglion cell death
por: Nadal-Nicolás, Francisco M., et al.
Publicado: (2017)

The retina of the lab rat: focus on retinal ganglion cells and photoreceptors
por: Galindo-Romero, Caridad, et al.
Publicado: (2022)

Comparative Analysis of Retinal Organotypic Cultures and In Vivo Axotomized Retinas
por: González-Riquelme, María José, et al.
Publicado: (2023)

Neuroprotection by α2-Adrenergic Receptor Stimulation after Excitotoxic Retinal Injury: A Study of the Total Population of Retinal Ganglion Cells and Their Distribution in the Chicken Retina
por: Galindo-Romero, Caridad, et al.
Publicado: (2016)

Immune recognition of syngeneic, allogeneic and xenogeneic stromal cell transplants in healthy retinas
por: Norte-Muñoz, María, et al.
Publicado: (2022)

Ly6c as a New Marker of Mouse Blood Vessels: Qualitative and Quantitative Analyses on Intact and Ischemic Retinas
por: Martínez-Carmona, Marina, et al.
Publicado: (2021)

Mesenchymal stromal cell therapy for damaged retinal ganglion cells, is gold all that glitters?
por: Lucas-Ruiz, Fernando, et al.
Publicado: (2019)

Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2014)

Pan-retinal ganglion cell markers in mice, rats, and rhesus macaques
por: Nadal-Nicolás, Francisco M., et al.
Publicado: (2023)

Role of microglial cells in photoreceptor degeneration
por: Di Pierdomenico, Johnny, et al.
Publicado: (2019)

Interplay between mesenchymal stromal cells and the immune system after transplantation: implications for advanced cell therapy in the retina
por: Norte-Muñoz, María, et al.
Publicado: (2023)

Tracing the retina to analyze the integrity and phagocytic capacity of the retinal pigment epithelium
por: Valiente-Soriano, Francisco J., et al.
Publicado: (2020)

Valproic Acid Reduces Neuroinflammation to Provide Retinal Ganglion Cell Neuroprotection in the Retina Axotomy Model
por: Tribble, James R., et al.
Publicado: (2022)

Coordinated Intervention of Microglial and Müller Cells in Light-Induced Retinal Degeneration
por: Di Pierdomenico, Johnny, et al.
Publicado: (2020)

Unraveling Axon Guidance during Axotomy and Regeneration
por: Domínguez-Romero, Miguel E., et al.
Publicado: (2021)

Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling
por: Nagendran, Tharkika, et al.
Publicado: (2017)

Activation of adenosine A(3) receptor protects retinal ganglion cells from degeneration induced by ocular hypertension
por: Boia, Raquel, et al.
Publicado: (2020)

Editorial: Molecular and cellular players of axonal regeneration in injured CNS
por: Santiago, Ana Raquel, et al.
Publicado: (2023)

Microglia in mouse retina contralateral to experimental glaucoma exhibit multiple signs of activation in all retinal layers
por: Rojas, Blanca, et al.
Publicado: (2014)

Short and long term axotomy-induced ERG changes in albino and pigmented rats
por: Alarcón-Martínez, Luis, et al.
Publicado: (2009)

IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma
por: Gallego, Beatriz I, et al.
Publicado: (2012)

In vivo Laser Axotomy in C. elegans
por: Byrne, Alexandra B., et al.
Publicado: (2011)

Calcium in Neuronal and Glial Response to Axotomy
por: Khaitin, Andrey
Publicado: (2021)

Rod-Like Microglia Are Restricted to Eyes with Laser-Induced Ocular Hypertension but Absent from the Microglial Changes in the Contralateral Untreated Eye
por: de Hoz, Rosa, et al.
Publicado: (2013)

7,8-Dihydroxiflavone Protects Adult Rat Axotomized Retinal Ganglion Cells through MAPK/ERK and PI3K/AKT Activation
por: Galindo-Romero, Caridad, et al.
Publicado: (2021)

Automatic Counting of Microglial Cells in Healthy and Glaucomatous Mouse Retinas
por: de Gracia, Pablo, et al.
Publicado: (2015)

Bilateral Nerve Alterations in a Unilateral Experimental Neurotrophic Keratopathy Model: A Lateral Conjunctival Approach for Trigeminal Axotomy
por: Yamaguchi, Takefumi, et al.
Publicado: (2013)

Intrinsic response of thoracic propriospinal neurons to axotomy
por: Siebert, Justin R, et al.
Publicado: (2010)

Microglial mitogens are produced in the developing and injured mammalian brain
Publicado: (1991)

Unilateral temporomandibular joint ankylosis with contralateral aplasia
por: Singh, Nimisha, et al.
Publicado: (2013)

Contralateral Eyebrow Approach for Unilateral Suprasellar Meningioma
por: Aldea, Sorin, et al.
Publicado: (2018)

Shared and Differential Retinal Responses against Optic Nerve Injury and Ocular Hypertension
por: Vidal-Sanz, Manuel, et al.
Publicado: (2017)

The senescent vision: dysfunction or neuronal loss?
por: Nadal-Nicolás, Francisco M., et al.
Publicado: (2018)

Retinal compensatory changes after light damage in albino mice
por: Montalbán-Soler, Luis, et al.
Publicado: (2012)

Death Commitment Point Is Advanced by Axotomy in Sympathetic Neurons
por: Fletcher, Graham C., et al.
Publicado: (2000)

Intravitreal fluorogold tracing as a method to label retinal neurons and the retinal pigment epithelium
por: Valiente-Soriano, Francisco Javier, et al.
Publicado: (2021)

Müller cell degeneration and microglial dysfunction in the Alzheimer’s retina
por: Xu, Qinyuan Alis, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_319j9ejlmsvm4o7qqab7ft3bhr