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Association between the exposure to anti-angiogenic agents and tumour immune microenvironment in advanced gastrointestinal stromal tumours

BACKGROUND: Tumour immune microenvironment (TIME) of gastrointestinal stromal tumours (GISTs) is largely unknown. METHODS: A total of 81 surgical specimens from 67 patients with advanced GISTs were categorised into treatment groups: tyrosine kinase inhibitor (TKI)-naive, n = 20; imatinib-progressed...

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Detalles Bibliográficos
Autores principales: Yoo, Changhoon, Ryu, Yeon-mi, Kim, Sang-Yeob, Kim, Jihun, Ock, Chan Young, Ryu, Min-Hee, Kang, Yoon-Koo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888806/
https://www.ncbi.nlm.nih.gov/pubmed/31607749
http://dx.doi.org/10.1038/s41416-019-0596-1