Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort

BACKGROUND: Guidelines remain unclear over whether patients with early stage oral cancer without overt neck disease benefit from upfront elective neck dissection (END), particularly those with the smallest tumours. METHODS: We conducted a randomised trial of patients with stage T1/T2 N0 disease, who...

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Detalles Bibliográficos
Autores principales: Hutchison, Iain L., Ridout, Fran, Cheung, Sharon M. Y., Shah, Neil, Hardee, Peter, Surwald, Christian, Thiruchelvam, Janavikulam, Cheng, Leo, Mellor, Tim K., Brennan, Peter A., Baldwin, Andrew J., Shaw, Richard J., Halfpenny, Wayne, Danford, Martin, Whitley, Simon, Smith, Graham, Bailey, Malcolm W., Woodwards, Bob, Patel, Manu, McManners, Joseph, Chan, Chi-Hwa, Burns, Andrew, Praveen, Prav, Camilleri, Andrew C., Avery, Chris, Putnam, Graham, Jones, Keith, Webster, Keith, Smith, William P., Edge, Colin, McVicar, Iain, Grew, Nick, Hislop, Stuart, Kalavrezos, Nicholas, Martin, Ian C., Hackshaw, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888839/
https://www.ncbi.nlm.nih.gov/pubmed/31611612
http://dx.doi.org/10.1038/s41416-019-0587-2

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