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An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s
Information about substrate and product selectivity is critical for understanding the function of cytochrome P450 monooxygenases. In addition, comprehensive understanding of changes in substrate selectivity of P450 upon amino acid mutation would enable the design and creation of engineered P450s wit...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888865/ https://www.ncbi.nlm.nih.gov/pubmed/31792277 http://dx.doi.org/10.1038/s41598-019-54473-8 |