An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s

Information about substrate and product selectivity is critical for understanding the function of cytochrome P450 monooxygenases. In addition, comprehensive understanding of changes in substrate selectivity of P450 upon amino acid mutation would enable the design and creation of engineered P450s wit...

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Detalles Bibliográficos
Autores principales: Kanoh, Naoki, Kawamata-Asano, Ayano, Suzuki, Kana, Takahashi, Yusuke, Miyazawa, Takeshi, Nakamura, Takemichi, Moriya, Takashi, Hirano, Hiroyuki, Osada, Hiroyuki, Iwabuchi, Yoshiharu, Takahashi, Shunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888865/
https://www.ncbi.nlm.nih.gov/pubmed/31792277
http://dx.doi.org/10.1038/s41598-019-54473-8

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