Selective inhibition of low-affinity memory CD8(+) T cells by corticosteroids

Patients treated with immune checkpoint blockade (ICB) sometimes experience immune-related adverse events (irAEs), requiring immuno-suppressive drugs such as corticosteroids despite the possibility that immunosuppression may impair the antitumor effects of ICB. Here, we address the dilemma of using...

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Detalles Bibliográficos
Autores principales: Tokunaga, Akihiro, Sugiyama, Daisuke, Maeda, Yuka, Warner, Allison Betof, Panageas, Katherine S., Ito, Sachiko, Togashi, Yosuke, Sakai, Chika, Wolchok, Jedd D., Nishikawa, Hiroyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888983/
https://www.ncbi.nlm.nih.gov/pubmed/31537643
http://dx.doi.org/10.1084/jem.20190738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888983/
https://www.ncbi.nlm.nih.gov/pubmed/31537643
http://dx.doi.org/10.1084/jem.20190738

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