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Gene fusions and chimeric RNAs, and their implications in cancer

Gene fusions are appreciated as ideal cancer biomarkers and therapeutic targets. Chimeric RNAs are traditionally thought to be products of gene fusions, and thus, also cancer-specific. Recent research has demonstrated that chimeric RNAs can be generated by intergenic splicing in the absence of gene...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Li, Xiaorong, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889028/
https://www.ncbi.nlm.nih.gov/pubmed/31832518
http://dx.doi.org/10.1016/j.gendis.2019.08.002