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DPP8 is a novel therapeutic target for multiple myeloma

Dipeptidyl peptidases (DPPs) are proteolytic enzymes that are ideal therapeutic targets in human diseases. Indeed, DPP4 inhibitors are widely used in clinical practice as anti-diabetic agents. In this paper, we show that DPP4 inhibitors also induced cell death in multiple human myeloma cells. Among...

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Detalles Bibliográficos
Autores principales: Sato, Tsutomu, Tatekoshi, Ayumi, Takada, Kohichi, Iyama, Satoshi, Kamihara, Yusuke, Jawaid, Paras, Rehman, Mati Ur, Noguchi, Kyo, Kondo, Takashi, Kajikawa, Sayaka, Arita, Kotaro, Wada, Akinori, Murakami, Jun, Arai, Miho, Yasuda, Ichiro, Dang, Nam H., Hatano, Ryo, Iwao, Noriaki, Ohnuma, Kei, Morimoto, Chikao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889119/
https://www.ncbi.nlm.nih.gov/pubmed/31792328
http://dx.doi.org/10.1038/s41598-019-54695-w