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Prognostic relevance of the Golgi mannosidase MAN1A1 in ovarian cancer: impact of N-glycosylation on tumour cell aggregation

BACKGROUND: Maturation of complex N-glycans involves the action of Golgi mannosidases and plays a major role in cancer progression. We recently showed a favourable prognostic role of α-mannosidase MAN1A1 in breast cancer mainly caused by alteration of certain adhesion molecules. METHODS: We analysed...

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Detalles Bibliográficos
Autores principales: Hamester, Fabienne, Legler, Karen, Wichert, Beatrice, Kelle, Nicole, Eylmann, Kathrin, Rossberg, Maila, Ding, Yi, Kürti, Sascha, Schmalfeldt, Barbara, Milde-Langosch, Karin, Oliveira-Ferrer, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889143/
https://www.ncbi.nlm.nih.gov/pubmed/31659304
http://dx.doi.org/10.1038/s41416-019-0607-2