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Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir

Combination antiretroviral therapy (cART) prevents HIV-1 replication but does not eliminate the latent reservoir and cure the infection. Type I interferons (IFN) mediate antiviral effects through different mechanisms than cART. We previously showed that IFNα14 is the most potent IFNα subtype against...

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Detalles Bibliográficos
Autores principales:	Sutter, Kathrin, Lavender, Kerry J., Messer, Ronald J., Widera, Marek, Williams, Katie, Race, Brent, Hasenkrug, Kim J., Dittmer, Ulf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889145/ https://www.ncbi.nlm.nih.gov/pubmed/31792317 http://dx.doi.org/10.1038/s41598-019-54650-9

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