Tumour cell-derived debris and IgG synergistically promote metastasis of pancreatic cancer by inducing inflammation via tumour-associated macrophages

BACKGROUND: The progression and metastasis of pancreatic ductal adenocarcinoma (PDAC) is highly dependent on the tumour microenvironment. Most tumour-associated macrophages (TAMs) are M2 phenotype macrophages, which normally show anti-inflammatory functions in numerous disorders. Previously, we foun...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Wang, Jianxin, Zhang, Qi, Zhang, Jingying, Lou, Yu, Yang, Jiaqi, Chen, Yiwen, Wei, Tao, Zhang, Jian, Fu, Qihan, Ye, Mao, Zhang, Xiaozhen, Dang, Xiaowei, Liang, Tingbo, Bai, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889176/
https://www.ncbi.nlm.nih.gov/pubmed/31588122
http://dx.doi.org/10.1038/s41416-019-0595-2

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