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The ArfGAP ASAP1 Controls Actin Stress Fiber Organization via Its N-BAR Domain

ASAP1 is a multi-domain ArfGAP that controls cell migration, spreading, and focal adhesion dynamics. Although its GAP activity contributes to remodeling of the actin cytoskeleton, it does not fully explain all cellular functions of ASAP1. Here we find that ASAP1 regulates actin filament assembly dir...

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Detalles Bibliográficos
Autores principales:	Gasilina, Anjelika, Vitali, Teresa, Luo, Ruibai, Jian, Xiaoying, Randazzo, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889188/ https://www.ncbi.nlm.nih.gov/pubmed/31785555 http://dx.doi.org/10.1016/j.isci.2019.11.015

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