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Molecular mechanisms of congenital heart disease in down syndrome
Down syndrome (DS), as a typical genomic aneuploidy, is a common cause of various birth defects, among which is congenital heart disease (CHD). 40–60% neonates with DS have some kinds of CHD. However, the molecular pathogenic mechanisms of DS associated CHD are still not fully understood. This revie...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889238/ https://www.ncbi.nlm.nih.gov/pubmed/31832516 http://dx.doi.org/10.1016/j.gendis.2019.06.007 |