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Molecular mechanisms of congenital heart disease in down syndrome

Down syndrome (DS), as a typical genomic aneuploidy, is a common cause of various birth defects, among which is congenital heart disease (CHD). 40–60% neonates with DS have some kinds of CHD. However, the molecular pathogenic mechanisms of DS associated CHD are still not fully understood. This revie...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Liu, Lingjuan, Tian, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889238/
https://www.ncbi.nlm.nih.gov/pubmed/31832516
http://dx.doi.org/10.1016/j.gendis.2019.06.007