Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans

Sex differences in opioid dependence (OD) are genetically influenced. We conducted genomewide gene-by-sex interaction scans for the DSM-IV diagnosis of OD in 8,387 African-American (AA) or European-American subjects (43.6% women; 4,715 OD subjects). Among AAs, 9 SNPs were genome-wide significant at...

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Detalles Bibliográficos
Autores principales: Yang, Bao-Zhu, Zhou, Hang, Cheng, Zhongshan, Kranzler, Henry R., Gelernter, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889277/
https://www.ncbi.nlm.nih.gov/pubmed/31792237
http://dx.doi.org/10.1038/s41598-019-53560-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889277/
https://www.ncbi.nlm.nih.gov/pubmed/31792237
http://dx.doi.org/10.1038/s41598-019-53560-0

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