Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer

BACKGROUND: CD3 +  and CD8 + T-cell infiltration were reported as positive predictive markers of survival in colorectal cancer (CRC) patients. Here, we demonstrate the prognostic significance of CD4 + and FOXP3 + T-cell densities in CRC. METHODS: We quantified the intratumoural densities of CD3 + ,...

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Detalles Bibliográficos
Autores principales: Kuwahara, Taichi, Hazama, Shoichi, Suzuki, Nobuaki, Yoshida, Shin, Tomochika, Shinobu, Nakagami, Yuki, Matsui, Hiroto, Shindo, Yoshitaro, Kanekiyo, Shinsuke, Tokumitsu, Yukio, Iida, Michihisa, Tsunedomi, Ryouichi, Takeda, Shigeru, Yoshino, Shigefumi, Okayama, Naoko, Suehiro, Yutaka, Yamasaki, Takahiro, Fujita, Tomonobu, Kawakami, Yutaka, Ueno, Tomio, Nagano, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889292/
https://www.ncbi.nlm.nih.gov/pubmed/31488881
http://dx.doi.org/10.1038/s41416-019-0559-6

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