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The Effect of pH on Antibiotic Efficacy against Coxiella burnetii in Axenic Media
Coxiella burnetii, the etiologic agent of Q fever, replicates in an intracellular phagolysosome with pH between 4 and 5. The impact of this low pH environment on antimicrobial treatment is not well understood. An in vitro system for testing antibiotic susceptibility of C. burnetii in axenic media wa...
Autores principales: | Smith, Cody B., Evavold, Charles, Kersh, Gilbert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889355/ https://www.ncbi.nlm.nih.gov/pubmed/31792307 http://dx.doi.org/10.1038/s41598-019-54556-6 |
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