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The Effect of pH on Antibiotic Efficacy against Coxiella burnetii in Axenic Media

Coxiella burnetii, the etiologic agent of Q fever, replicates in an intracellular phagolysosome with pH between 4 and 5. The impact of this low pH environment on antimicrobial treatment is not well understood. An in vitro system for testing antibiotic susceptibility of C. burnetii in axenic media wa...

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Detalles Bibliográficos
Autores principales: Smith, Cody B., Evavold, Charles, Kersh, Gilbert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889355/
https://www.ncbi.nlm.nih.gov/pubmed/31792307
http://dx.doi.org/10.1038/s41598-019-54556-6

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