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A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells
Pancreatic endocrine cell differentiation is orchestrated by the action of transcription factors that operate in a gene regulatory network to activate endocrine lineage genes and repress lineage-inappropriate genes. MicroRNAs (miRNAs) are important modulators of gene expression, yet their role in en...
Autores principales: | Jin, Wen, Mulas, Francesca, Gaertner, Bjoern, Sui, Yinghui, Wang, Jinzhao, Matta, Ileana, Zeng, Chun, Vinckier, Nicholas, Wang, Allen, Nguyen-Ngoc, Kim-Vy, Chiou, Joshua, Kaestner, Klaus H., Frazer, Kelly A., Carrano, Andrea C., Shih, Hung-Ping, Sander, Maike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889369/ https://www.ncbi.nlm.nih.gov/pubmed/31733514 http://dx.doi.org/10.1016/j.isci.2019.10.063 |
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