A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion

Field cancerization is a premalignant process marked by clones of oncogenic mutations spreading through the epithelium. The timescales of intestinal field cancerization can be variable and the mechanisms driving the rapid spread of oncogenic clones are unknown. Here we use a Cancer rainbow (Crainbow...

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Detalles Bibliográficos
Autores principales: Boone, Peter G., Rochelle, Lauren K., Ginzel, Joshua D., Lubkov, Veronica, Roberts, Wendy L., Nicholls, P. J., Bock, Cheryl, Flowers, Mei Lang, von Furstenberg, Richard J., Stripp, Barry R., Agarwal, Pankaj, Borowsky, Alexander D., Cardiff, Robert D., Barak, Larry S., Caron, Marc G., Lyerly, H. Kim, Snyder, Joshua C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889384/
https://www.ncbi.nlm.nih.gov/pubmed/31792216
http://dx.doi.org/10.1038/s41467-019-13330-y

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