Identification of the amino acid residue responsible for the myricetin sensitivity of human proton-coupled folate transporter

Human proton-coupled folate transporter (hPCFT/SLC46A1) has recently been found to be inhibited by myricetin by a sustained mechanism, raising a concern that the inhibition might lead to malabsorption of folates in the intestine, where hPCFT works for their epithelial uptake. However, rat PCFT (rPCF...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamashiro, Takahiro, Yasujima, Tomoya, Ohta, Kinya, Inoue, Katsuhisa, Yuasa, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889420/
https://www.ncbi.nlm.nih.gov/pubmed/31792273
http://dx.doi.org/10.1038/s41598-019-54367-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889420/
https://www.ncbi.nlm.nih.gov/pubmed/31792273
http://dx.doi.org/10.1038/s41598-019-54367-9

Ejemplares similares