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Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea
BACKGROUND: The global burden of seasonal influenza on medical care has been one of the greatest in the pediatric population. The attention drawn to influenza B was relatively low compared to influenza A, probably because the influenza B virus was thought to be less virulent and have a lower pandemi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889424/ https://www.ncbi.nlm.nih.gov/pubmed/31796033 http://dx.doi.org/10.1186/s12887-019-1862-3 |
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author | Oh, Yu Na Kim, San Choi, Young Bae Woo, Sung Il Hahn, Youn-Soo Lee, Joon Kee |
author_facet | Oh, Yu Na Kim, San Choi, Young Bae Woo, Sung Il Hahn, Youn-Soo Lee, Joon Kee |
author_sort | Oh, Yu Na |
collection | PubMed |
description | BACKGROUND: The global burden of seasonal influenza on medical care has been one of the greatest in the pediatric population. The attention drawn to influenza B was relatively low compared to influenza A, probably because the influenza B virus was thought to be less virulent and have a lower pandemic potential. This study aimed to compare the clinical features of influenza A and B in children. METHODS: This retrospective study included children diagnosed and treated for influenza as inpatients or outpatients during the 2017/18 influenza season at a tertiary referral hospital. Data regarding clinical characteristics, diagnoses, laboratory results, and vaccination histories were collected and reviewed. RESULTS: Over the study period, 128 patients with influenza A and 109 patients with influenza B were identified. The mean age of patients with influenza B was significantly higher than that of patients with influenza A (5.6 ± 4.4 vs 4.1 ± 4.4 years, p = 0.010). Fever was the most common manifestation of influenza followed by respiratory symptoms. No single symptom was specifically associated with either type of influenza. The total duration of fever (4.3 ± 2.3 vs 3.7 ± 2.6 days), ‘time from fever onset to initiation of antivirals’, and ‘time from initiation of antivirals to defervescence’ were similar between the two influenza types, even though all three time periods tended to be longer for influenza B. The platelet counts and proportions of neutrophils were higher for influenza A than for influenza B infections, although the values were within normal limits for both influenza types. CONCLUSIONS: We found overall clinical similarities between influenza A and B with no less clinical significance or severity of influenza B compared to those of influenza A. Equal levels of awareness and attention should be paid to both influenza types. |
format | Online Article Text |
id | pubmed-6889424 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-68894242019-12-11 Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea Oh, Yu Na Kim, San Choi, Young Bae Woo, Sung Il Hahn, Youn-Soo Lee, Joon Kee BMC Pediatr Research Article BACKGROUND: The global burden of seasonal influenza on medical care has been one of the greatest in the pediatric population. The attention drawn to influenza B was relatively low compared to influenza A, probably because the influenza B virus was thought to be less virulent and have a lower pandemic potential. This study aimed to compare the clinical features of influenza A and B in children. METHODS: This retrospective study included children diagnosed and treated for influenza as inpatients or outpatients during the 2017/18 influenza season at a tertiary referral hospital. Data regarding clinical characteristics, diagnoses, laboratory results, and vaccination histories were collected and reviewed. RESULTS: Over the study period, 128 patients with influenza A and 109 patients with influenza B were identified. The mean age of patients with influenza B was significantly higher than that of patients with influenza A (5.6 ± 4.4 vs 4.1 ± 4.4 years, p = 0.010). Fever was the most common manifestation of influenza followed by respiratory symptoms. No single symptom was specifically associated with either type of influenza. The total duration of fever (4.3 ± 2.3 vs 3.7 ± 2.6 days), ‘time from fever onset to initiation of antivirals’, and ‘time from initiation of antivirals to defervescence’ were similar between the two influenza types, even though all three time periods tended to be longer for influenza B. The platelet counts and proportions of neutrophils were higher for influenza A than for influenza B infections, although the values were within normal limits for both influenza types. CONCLUSIONS: We found overall clinical similarities between influenza A and B with no less clinical significance or severity of influenza B compared to those of influenza A. Equal levels of awareness and attention should be paid to both influenza types. BioMed Central 2019-12-03 /pmc/articles/PMC6889424/ /pubmed/31796033 http://dx.doi.org/10.1186/s12887-019-1862-3 Text en © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Oh, Yu Na Kim, San Choi, Young Bae Woo, Sung Il Hahn, Youn-Soo Lee, Joon Kee Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea |
title | Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea |
title_full | Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea |
title_fullStr | Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea |
title_full_unstemmed | Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea |
title_short | Clinical similarities between influenza A and B in children: a single-center study, 2017/18 season, Korea |
title_sort | clinical similarities between influenza a and b in children: a single-center study, 2017/18 season, korea |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889424/ https://www.ncbi.nlm.nih.gov/pubmed/31796033 http://dx.doi.org/10.1186/s12887-019-1862-3 |
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