Cargando…
Piperaquine concentration and malaria treatment outcomes in Ugandan children treated for severe malaria with intravenous Artesunate or quinine plus Dihydroartemisinin-Piperaquine
BACKGROUND: Treatment for severe malaria must be prompt with effective parenteral antimalarial drugs for at least 24 h to achieve fast parasite clearance, and when the patient can tolerate oral therapy, treatment should be completed with effective artemisinin based combination therapy (ACT) for comp...
Autores principales: | Byakika-Kibwika, Pauline, Ssenyonga, Ronald, Lamorde, Mohammed, Blessborn, Daniel, Tarning, Joel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889437/ https://www.ncbi.nlm.nih.gov/pubmed/31795967 http://dx.doi.org/10.1186/s12879-019-4647-2 |
Ejemplares similares
-
Efficacy of Quinine, Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine as Rescue Treatment for Uncomplicated Malaria in Ugandan Children
por: Yeka, Adoke, et al.
Publicado: (2013) -
Intravenous artesunate plus oral dihydroartemisinin–piperaquine or intravenous quinine plus oral quinine for optimum treatment of severe malaria: lesson learnt from a field hospital in Timika, Papua, Indonesia
por: Sikora, Silvester Alexandro, et al.
Publicado: (2019) -
Variable piperaquine exposure significantly impacts protective efficacy of monthly dihydroartemisinin-piperaquine for the prevention of malaria in Ugandan children
por: Sundell, Kerstin, et al.
Publicado: (2015) -
Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults
por: Byakika-Kibwika, Pauline, et al.
Publicado: (2012) -
Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trial
por: Byakika-Kibwika, Pauline, et al.
Publicado: (2017)