Cargando…

Apolipoprotein M and sphingosine-1-phosphate complex alleviates TNF-α-induced endothelial cell injury and inflammation through PI3K/AKT signaling pathway

BACKGROUND: In spite of the important role of Apolipoprotein-M (ApoM) and Sphingosine-1-Phosphate (S1P) played in atherosclerosis (AS), there was few related research reporting ApoM and S1P complex (ApoM-S1P) on biological activities of human umbilical vein endothelial cells (HUVECs). In this study,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yang, Tie, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889454/ https://www.ncbi.nlm.nih.gov/pubmed/31791242 http://dx.doi.org/10.1186/s12872-019-1263-4

Ejemplares similares

Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes
por: Christensen, Pernille M., et al.
Publicado: (2017)

Apolipoprotein M and Sphingosine-1-Phosphate: A Potentially Antidiabetic Tandem Carried by HDL
por: Yalcinkaya, Mustafa, et al.
Publicado: (2020)

Glycation of HDL Polymerizes Apolipoprotein M and Attenuates Its Capacity to Bind to Sphingosine 1-Phosphate
por: Kobayashi, Tamaki, et al.
Publicado: (2021)

The Apolipoprotein M–Sphingosine-1-Phosphate Axis: Biological Relevance in Lipoprotein Metabolism, Lipid Disorders and Atherosclerosis
por: Arkensteijn, Bas W. C., et al.
Publicado: (2013)

Sphingosine 1‐phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons
por: Frej, Cecilia, et al.
Publicado: (2016)

Apolipoprotein M Inhibits Angiogenic and Inflammatory Response by Sphingosine 1-Phosphate on Retinal Pigment Epithelium Cells
por: Terao, Ryo, et al.
Publicado: (2017)

Apolipoprotein M-bound sphingosine-1-phosphate regulates blood–brain barrier paracellular permeability and transcytosis
por: Mathiesen Janiurek, Mette, et al.
Publicado: (2019)

Association of apolipoprotein M and sphingosine-1-phosphate with brown adipose tissue after cold exposure in humans
por: Borup, Anna, et al.
Publicado: (2022)

Sphingosine 1-Phosphate and Apolipoprotein M Levels and Their Correlations with Inflammatory Biomarkers in Patients with Untreated Familial Hypercholesterolemia
por: Juhász, Lilla, et al.
Publicado: (2022)

Baicalein alleviates TNF-α-induced apoptosis of human nucleus pulposus cells through PI3K/AKT signaling pathway
por: Liu, Yang, et al.
Publicado: (2023)

Modulation of sphingosine-1-phosphate and apolipoprotein M levels in the plasma, liver and kidneys in streptozotocin-induced diabetic mice
por: Nojiri, Takahiro, et al.
Publicado: (2014)

Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment
por: Checa, Antonio, et al.
Publicado: (2015)

The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer
por: Hait, Nitai C., et al.
Publicado: (2017)

Inflammatory Conditions Disrupt Constitutive Endothelial Cell Barrier Stabilization by Alleviating Autonomous Secretion of Sphingosine 1-Phosphate
por: Jeya Paul, Jefri, et al.
Publicado: (2020)

The role of sphingosine‐1‐phosphate in inflammation and cancer progression
por: Nagahashi, Masayuki, et al.
Publicado: (2018)

Hepatic FoxOs link insulin signaling with plasma lipoprotein metabolism through an apolipoprotein M/sphingosine-1-phosphate pathway
por: Izquierdo, María Concepción, et al.
Publicado: (2022)

Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-α signalling pathways
por: Zhu, Wen, et al.
Publicado: (2022)

Sphingosine-1-Phosphate Improves the Biological Features of Mouse Bone Marrow-Derived EPCs Partially through PI3K/AKT/eNOS/NO Pathway
por: Wang, Xia, et al.
Publicado: (2019)

Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages
por: Yang, Tao, et al.
Publicado: (2022)

Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer
por: Xu, Guangmeng, et al.
Publicado: (2021)

Sphingosine 1-phosphate receptor 2 promotes the onset and progression of non-alcoholic fatty liver disease-related hepatocellular carcinoma through the PI3K/AKT/mTOR pathway
por: Wang, Ganggang, et al.
Publicado: (2023)

Sphingosine-1-Phosphate Receptor 3 Mediates Sphingosine-1-Phosphate Induced Release of Weibel-Palade Bodies from Endothelial Cells
por: van Hooren, Kathinka W. E. M., et al.
Publicado: (2014)

Apolipoprotein D alleviates glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells via the PI3K/Akt pathway
por: Yu, Rong-Hua, et al.
Publicado: (2020)

Emerging Role of Sphingosine-1-phosphate in Inflammation, Cancer, and Lymphangiogenesis
por: Huang, Wei-Ching, et al.
Publicado: (2013)

Role of Sphingosine 1-Phosphate Signalling Axis in Muscle Atrophy Induced by TNFα in C2C12 Myotubes
por: Bernacchioni, Caterina, et al.
Publicado: (2021)

The Combination Treatment of Curcumin and Probucol Protects Chondrocytes from TNF-α Induced Inflammation by Enhancing Autophagy and Reducing Apoptosis via the PI3K-Akt-mTOR Pathway
por: Han, Guangtao, et al.
Publicado: (2021)

Endothelial Spns2 and ApoM Regulation of Vascular Tone and Hypertension Via Sphingosine‐1‐Phosphate
por: Del Gaudio, Ilaria, et al.
Publicado: (2021)

The Role of Sphingolipids and Sphingosine-1-phosphate—Sphingosine-1-phosphate-receptor Signaling in Psoriasis
por: Masuda-Kuroki, Kana, et al.
Publicado: (2023)

PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis
por: Liu, Songyang, et al.
Publicado: (2019)

Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy
por: Lu, Rui, et al.
Publicado: (2022)

Vitamin B6 prevents excessive inflammation by reducing accumulation of sphingosine‐1‐phosphate in a sphingosine‐1‐phosphate lyase–dependent manner
por: Du, Xialin, et al.
Publicado: (2020)

DT-13 Ameliorates TNF-α-Induced Vascular Endothelial Hyperpermeability via Non-Muscle Myosin IIA and the Src/PI3K/Akt Signaling Pathway
por: Zhang, Yuanyuan, et al.
Publicado: (2017)

The PI3K/Akt Pathway in Meta-Inflammation
por: Acosta-Martinez, Maricedes, et al.
Publicado: (2022)

Sphingosine 1-Phosphate and Atherosclerosis
por: Kurano, Makoto, et al.
Publicado: (2018)

Sphingosine-1-Phosphate Aggravates Antigen-Induced Airway Inflammation in Mice
por: Chiba, Yoshihiko, et al.
Publicado: (2010)

Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy
por: Cartier, Andreane, et al.
Publicado: (2020)

Sphingosine-1-phosphate and its receptors in vascular endothelial and lymphatic barrier function
por: Weigel, Cynthia, et al.
Publicado: (2023)

Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer’s Disease and Control Mice
por: den Hoedt, Sandra, et al.
Publicado: (2021)

Alleviative effects of α‐lipoic acid on muscle atrophy via the modulation of TNF‐α/JNK and PI3K/AKT pathways in high‐fat diet and streptozotocin‐induced type 2 diabetic rats
por: Ko, Chih‐Yuan, et al.
Publicado: (2023)

Icariin alleviates osteoarthritis by regulating autophagy of chondrocytes by mediating PI3K/AKT/mTOR signaling
por: Tang, Yanghua, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rdtig6cejlierqobr9of6qo1a0