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Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster

OBJECTIVE: Fibroblast growth factor 21 (FGF21) has been shown to rapidly lower body weight in the Siberian hamster, a preclinical model of adiposity. This induced negative energy balance mediated by FGF21 is associated with both lowered caloric intake and increased energy expenditure. Previous resea...

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Detalles Bibliográficos
Autores principales: Lewis, Jo E., Monnier, Chloe, Marshall, Hayley, Fowler, Maxine, Green, Rebecca, Cooper, Scott, Chiotellis, Aristeidis, Luckett, Jeni, Perkins, Alan C., Coskun, Tamer, Adams, Andrew C., Samms, Ricardo J., Ebling, Francis J.P., Tsintzas, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889485/
https://www.ncbi.nlm.nih.gov/pubmed/31918921
http://dx.doi.org/10.1016/j.molmet.2019.10.009