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HDAC2 hyperexpression alters hippocampal neuronal transcription and microglial activity in neuroinflammation-induced cognitive dysfunction

BACKGROUND: Inflammation can induce cognitive dysfunction in patients who undergo surgery. Previous studies have demonstrated that both acute peripheral inflammation and anaesthetic insults, especially isoflurane (ISO), are risk factors for memory impairment. Few studies are currently investigating...

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Detalles Bibliográficos
Autores principales: Sun, Xiao-Yu, Zheng, Teng, Yang, Xiu, Liu, Le, Gao, Shen-Shen, Xu, Han-Bing, Song, Yu-Tong, Tong, Kun, Yang, Li, Gao, Ya, Wu, Tong, Hao, Jing-Ru, Lu, Chen, Ma, Tao, Gao, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889553/
https://www.ncbi.nlm.nih.gov/pubmed/31796106
http://dx.doi.org/10.1186/s12974-019-1640-z

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