Differential Cell Susceptibilities to Kras(G12D) in the Setting of Obstructive Chronic Pancreatitis

BACKGROUND & AIMS: Activating mutation of the KRAS gene is common in some cancers, such as pancreatic cancer, but rare in other cancers. Chronic pancreatitis is a predisposing condition for pancreatic ductal adenocarcinoma (PDAC), but how it synergizes with KRAS mutation is not known. METHODS: W...

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Detalles Bibliográficos
Autores principales: Shi, Chanjuan, Pan, Fong Cheng, Kim, Jessica N., Washington, M. Kay, Padmanabhan, Chandrasekhar, Meyer, Christian T., Kopp, Janel L., Sander, Maike, Gannon, Maureen, Beauchamp, R. Daniel, Wright, Christopher V., Means, Anna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889613/
https://www.ncbi.nlm.nih.gov/pubmed/31310834
http://dx.doi.org/10.1016/j.jcmgh.2019.07.001

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