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Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis
BACKGROUND: Prostate cancer (Pca) remains one of the leading adult malignancies. PTEN (Phosphatase and Tensin Homolog) mutant is the top common mutated genes in prostate cancer, which makes it a promising biomarker in future individualized treatment. METHODS: We obtained gene expression data of pros...
Autores principales: | Sun, Jian, Li, Shugen, Wang, Fei, Fan, Caibin, Wang, Jianqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889628/ https://www.ncbi.nlm.nih.gov/pubmed/31791268 http://dx.doi.org/10.1186/s12881-019-0923-7 |
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