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Sample size re-estimation in crossover trials: application to the AIM HY-INFORM study
BACKGROUND: Crossover designs are commonly utilised in randomised controlled trials investigating treatments for long-term chronic illnesses. One problem with this design is its inherent repeated measures necessitate the availability of an estimate of the within-person standard deviation (SD) to per...
Autores principales: | Wych, Julie, Grayling, Michael J., Mander, Adrian P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889633/ https://www.ncbi.nlm.nih.gov/pubmed/31791376 http://dx.doi.org/10.1186/s13063-019-3724-6 |
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