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Multiple nivolumab-induced CNS demyelination with spontaneous resolution in an asymptomatic metastatic melanoma patient

BACKGROUND: Immune checkpoint inhibitors (ICPis) have revolutionised the treatment of melanoma by significantly increasing survival rates and disease control. However, ICPis can have specific immune-related adverse events, including rare but severe neurological toxicity. CASE PRESENTATION: We report...

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Detalles Bibliográficos
Autores principales: Pillonel, Vincent, Dunet, Vincent, Hottinger, Andreas F., Berthod, Gregoire, Schiappacasse, Luis, Peters, Solange, Michielin, Olivier, Aedo-Lopez, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889661/
https://www.ncbi.nlm.nih.gov/pubmed/31791418
http://dx.doi.org/10.1186/s40425-019-0818-3