NPAS2 Contributes to Liver Fibrosis by Direct Transcriptional Activation of Hes1 in Hepatic Stellate Cells

Recently, emerging evidence shows that dysregulation of circadian genes is closely associated with liver fibrosis. However, how dysregulation of circadian genes promotes liver fibrosis is unknown. In this study, we show that neuronal PAS domain protein 2 (NPAS2), one of the core circadian molecules...

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Detalles Bibliográficos
Autores principales: Yang, Tao, Yuan, Peng, Yang, Yi, Liang, Ning, Wang, Qian, Li, Jing, Lu, Rui, Zhang, Hongxin, Mu, Jiao, Yan, Zhaoyong, Chang, Hulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889679/
https://www.ncbi.nlm.nih.gov/pubmed/31778954
http://dx.doi.org/10.1016/j.omtn.2019.10.025

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