Successful treatment of Post-orgasmic illness syndrome with human chorionic gonadotropin

Post-orgasmic illness syndrome (POIS) is an uncommon condition in which men experience debilitating symptoms following orgasm, including anxiety, weakness, and lassitude. The etiology is unknown, and treatment challenging. We present a 25y man with POIS since puberty. He dreaded ejaculation due to h...

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Detalles Bibliográficos
Autores principales: Bolanos, Jose, Morgentaler, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Andrology and Fertility
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889685/
https://www.ncbi.nlm.nih.gov/pubmed/31832334
http://dx.doi.org/10.1016/j.eucr.2019.101078
Descripción
Sumario:Post-orgasmic illness syndrome (POIS) is an uncommon condition in which men experience debilitating symptoms following orgasm, including anxiety, weakness, and lassitude. The etiology is unknown, and treatment challenging. We present a 25y man with POIS since puberty. He dreaded ejaculation due to his subsequent symptoms. Multiple prior treatments had failed. Blood tests revealed testosterone (T) deficiency. hCG was prescribed. At 6 weeks T levels normalized with near-complete resolution of symptoms. This successful result argues for hormonal investigation in men with POIS, and a trial of hCG or T therapy if total or free T is low or borderline.

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