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Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision

INTRODUCTION: Although the Kaposi sarcoma (KS) is one of the AIDS defining entity and seen in almost one third of HIV infected patients with low CD4 cell counts, it is not uncommon in HIV seronegative persons, but genital KS is rare, particularly in people without risk factors for HIV infection. Iso...

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Autores principales: Alamri, Abdulaziz, Adiga, B. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889700/
https://www.ncbi.nlm.nih.gov/pubmed/31827596
http://dx.doi.org/10.1186/s13027-019-0261-6
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author Alamri, Abdulaziz
Adiga, B. K.
author_facet Alamri, Abdulaziz
Adiga, B. K.
author_sort Alamri, Abdulaziz
collection PubMed
description INTRODUCTION: Although the Kaposi sarcoma (KS) is one of the AIDS defining entity and seen in almost one third of HIV infected patients with low CD4 cell counts, it is not uncommon in HIV seronegative persons, but genital KS is rare, particularly in people without risk factors for HIV infection. Isolated penile KS is an unusual manifestation, especially as solitary nodule with ulceration, in HIV seronegative patient. CASE PRESENTATION: We report such a case of Kaposi sarcoma showing HHV-8 positivity in an elderly male Arabian patient with a delay in prompt diagnosis, but treated successfully with 3 3 years follow-up after limited local surgical excision. CONCLUSION: The general practitioners, venereologists and urologists should think of KS as a possibility in such lesion and consider early biopsy.
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spelling pubmed-68897002019-12-11 Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision Alamri, Abdulaziz Adiga, B. K. Infect Agent Cancer Short Report INTRODUCTION: Although the Kaposi sarcoma (KS) is one of the AIDS defining entity and seen in almost one third of HIV infected patients with low CD4 cell counts, it is not uncommon in HIV seronegative persons, but genital KS is rare, particularly in people without risk factors for HIV infection. Isolated penile KS is an unusual manifestation, especially as solitary nodule with ulceration, in HIV seronegative patient. CASE PRESENTATION: We report such a case of Kaposi sarcoma showing HHV-8 positivity in an elderly male Arabian patient with a delay in prompt diagnosis, but treated successfully with 3 3 years follow-up after limited local surgical excision. CONCLUSION: The general practitioners, venereologists and urologists should think of KS as a possibility in such lesion and consider early biopsy. BioMed Central 2019-12-02 /pmc/articles/PMC6889700/ /pubmed/31827596 http://dx.doi.org/10.1186/s13027-019-0261-6 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Alamri, Abdulaziz
Adiga, B. K.
Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision
title Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision
title_full Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision
title_fullStr Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision
title_full_unstemmed Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision
title_short Atypical presentation of classic Kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (HHV8) positivity and successfully treated with only local excision
title_sort atypical presentation of classic kaposi sarcoma in circumcised penis presenting as an ulcerative nodule with human herpesvirus 8 (hhv8) positivity and successfully treated with only local excision
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889700/
https://www.ncbi.nlm.nih.gov/pubmed/31827596
http://dx.doi.org/10.1186/s13027-019-0261-6
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