Correlation of prechemotherapy urinary megalin ectodomain (A-megalin) levels with the development of cisplatin-induced nephrotoxicity: a prospective observational study

BACKGROUND: Cisplatin is a potent chemotherapeutic agent used to treat a variety of solid tumors. One of the major side effects of cisplatin is dose-limiting nephrotoxicity. We recently demonstrated that the renal uptake of cisplatin and resultant cisplatin-induced nephrotoxicity are mediated in par...

Descripción completa

Detalles Bibliográficos
Autores principales: Shoji, Satoshi, Hosojima, Michihiro, Kabasawa, Hideyuki, Kondo, Rie, Miura, Satoru, Watanabe, Satoshi, Aoki, Nobumasa, Kaseda, Ryohei, Kuwahara, Shoji, Tanabe, Naohito, Hirayama, Yoshiaki, Narita, Ichiei, Kikuchi, Toshiaki, Kagamu, Hiroshi, Saito, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889728/
https://www.ncbi.nlm.nih.gov/pubmed/31791266
http://dx.doi.org/10.1186/s12885-019-6398-2

Ejemplares similares

Ejemplares similares