Cargando…

G protein-coupled estrogen receptor-1 agonist induces chemotherapeutic effect via ER stress signaling in gastric cancer

G protein-coupled estrogen receptor (GPER) is known to play an important role in hormone-associated cancers. G-1, a novel synthetic GPER agonist, has been reported to exhibit anti-carcinogenic properties. However, the chemotherapeutic mechanism of GPER is yet unclear. Here, we evaluated GPER express...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Seon-Jin, Kim, Tae Woo, Park, Gyeong Lim, Hwang, Yo Sep, Cho, Hee Jun, Kim, Jong-Tae, Lee, Hee Gu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889890/ https://www.ncbi.nlm.nih.gov/pubmed/31234952 http://dx.doi.org/10.5483/BMBRep.2019.52.11.007

Ejemplares similares

G-protein Coupled Estrogen Receptor (GPER/GPR30) and Women's Health
por: Kim, Mi-Jin, et al.
Publicado: (2015)

Functions and physiological roles of two types of estrogen receptors, ERα and ERβ, identified by estrogen receptor knockout mouse
por: Lee, Hye-Rim, et al.
Publicado: (2012)

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer
por: Kim, Tae Woo, et al.
Publicado: (2016)

Estrogen and G protein-coupled estrogen receptor agonist G-1 cause relaxation of human gallbladder
por: Lee, Ming-Che, et al.
Publicado: (2016)

Chrysin-Induced G Protein-Coupled Estrogen Receptor Activation Suppresses Pancreatic Cancer
por: Lim, Hyun Kyung, et al.
Publicado: (2022)

G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells
por: Vo, Diep-Khanh Ho, et al.
Publicado: (2019)

Erastin Inhibits Septic Shock and Inflammatory Gene Expression via Suppression of the NF-κB Pathway
por: Oh, Byung Moo, et al.
Publicado: (2019)

6-Shogaol Overcomes Gefitinib Resistance via ER Stress in Ovarian Cancer Cells
por: Kim, Tae Woo, et al.
Publicado: (2023)

ER71/ETV2 Promotes Hair Regeneration from Chemotherapeutic Drug-Induced Hair Loss by Enhancing Angiogenesis
por: Lee, Tae-Jin, et al.
Publicado: (2021)

DNA Replication and Sister Chromatid Cohesion 1 (DSCC1) of the Replication Factor Complex CTF18-RFC is Critical for Colon Cancer Cell Growth
por: Kim, Jong-Tae, et al.
Publicado: (2019)

Mucinous Borderline Ovarian Tumor in Very Old Aged Postmenopausal Woman
por: Lee, Seung-Hee, et al.
Publicado: (2015)

Targeting ER Stress with Saikosaponin A to Overcome Resistance under Radiation in Gastric Cancer Cells
por: Kim, Tae Woo
Publicado: (2023)

G Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Mantle Cell Lymphoma Growth in Preclinical Models
por: Zhou, Lixia, et al.
Publicado: (2021)

Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification in gastric cancer cells
por: Kim, Tae Woo
Publicado: (2021)

Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1
por: Qi, Miaomiao, et al.
Publicado: (2021)

The G-protein-coupled estrogen receptor agonist G-1 suppresses proliferation of ovarian cancer cells by blocking tubulin polymerization
por: Wang, C, et al.
Publicado: (2013)

The G-Protein–Coupled Estrogen Receptor Agonist G-1 Inhibits Proliferation and Causes Apoptosis in Leukemia Cell Lines of T Lineage
por: Torres-López, Liliana, et al.
Publicado: (2022)

KLK6/PAR1 Axis Promotes Tumor Growth and Metastasis by Regulating Cross-Talk between Tumor Cells and Macrophages
por: Hwang, Yo Sep, et al.
Publicado: (2022)

G Protein-Coupled Estrogen Receptor-1 Is Involved in the Protective Effect of Protocatechuic Aldehyde against Endothelial Dysfunction
por: Kong, Byung Soo, et al.
Publicado: (2014)

Apigenin Induces Autophagy and Cell Death by Targeting EZH2 under Hypoxia Conditions in Gastric Cancer Cells
por: Kim, Tae Woo, et al.
Publicado: (2021)

Effects of Estrogen, an ERα Agonist and Raloxifene on Pressure Overload Induced Cardiac Hypertrophy
por: Westphal, Christina, et al.
Publicado: (2012)

Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism
por: Dunlap, Tareisha L., et al.
Publicado: (2017)

Bisphenol AF Is a Full Agonist for the Estrogen Receptor ERα but a Highly Specific Antagonist for ERβ
por: Matsushima, Ayami, et al.
Publicado: (2010)

Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells
por: Kim, Tae Woo, et al.
Publicado: (2018)

miR-302 Suppresses the Proliferation, Migration, and Invasion of Breast Cancer Cells by Downregulating ATAD2
por: Hwang, Yo Sep, et al.
Publicado: (2022)

G-Protein-Coupled Receptor 120 Mediates DHA-Induced Apoptosis by Regulating IP3R, ROS and, ER Stress Levels in Cisplatin-Resistant Cancer Cells
por: Shin, Jong-Il, et al.
Publicado: (2019)

Epigenetic modification of TLR4 promotes activation of NF-κB by regulating methyl-CpG-binding domain protein 2 and Sp1 in gastric cancer
por: Kim, Tae Woo, et al.
Publicado: (2015)

The G protein–coupled estrogen receptor agonist, G‐1, attenuates BK channel activation in cerebral arterial smooth muscle cells
por: Evanson, Kirk W., et al.
Publicado: (2018)

Comparison of estrogen receptor-α, progesterone receptor and calponin expression in gonadotrophin-releasing hormone agonist-sensitive and -resistant uterine fibroids
por: Kim, Eun Hee, et al.
Publicado: (2014)

The optimal chemotherapeutic regimen in D2-resected locally advanced gastric cancer: a propensity score-matched analysis
por: Hwang, Jun Eul, et al.
Publicado: (2017)

Estrogen receptor variant ER‐α36 promotes tamoxifen agonist activity in glioblastoma cells
por: Qu, Chao, et al.
Publicado: (2019)

Anti-tumor efficacy of fulvestrant in estrogen receptor positive gastric cancer
por: Yi, Jun Ho, et al.
Publicado: (2014)

Growth and Bone Mineral Density Changes in Ovariectomized Rats Treated with Estrogen Receptor Alpha or Beta Agonists
por: Kang, Byung Ho, et al.
Publicado: (2020)

Transcriptomic data of MCF-7 breast cancer cells treated with G1, a G-protein coupled estrogen receptor (GPER) agonist()
por: Pal, Uttariya, et al.
Publicado: (2022)

Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen
por: Lee, Yoot Mo, et al.
Publicado: (2007)

Collapsin response mediator protein 4 enhances the radiosensitivity of colon cancer cells through calcium-mediated cell signaling
por: Park, Sang Yoon, et al.
Publicado: (2021)

Predicting the chemotherapeutic response of colorectal cancer liver metastasis using shear-wave elastography
por: Bae, Jae Seok, et al.
Publicado: (2023)

Chemotherapeutic Effect of SR9009, a REV-ERB Agonist, on the Human Glioblastoma T98G Cells
por: Wagner, Paula M., et al.
Publicado: (2019)

Estrogen receptor alpha (ERα)–mediated coregulator binding and gene expression discriminates the toxic ERα agonist diethylstilbestrol (DES) from the endogenous ERα agonist 17β-estradiol (E2)
por: Adam, Aziza Hussein Bakheit, et al.
Publicado: (2020)

G-Protein-Coupled Estrogen Receptor Agonist Suppresses Airway Inflammation in a Mouse Model of Asthma through IL-10
por: Itoga, Masamichi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_3vghaa0oe9nmuaroc82hcqnj59